Question of the week. Does vaping cause Popcorn Lung?

Posted by DrMendelsohn on 17 August, 2017

Popcorn.jpgAnswer: NO

A 67-year old patient of mine quit smoking earlier this year by switching to an e-cigarette, an impressive achievement after 50 years of smoking 20 cigarettes a day. He found using an Innokin T22 with nicotine-free e-liquid '90% as satisfying as smoking'.

Recently a friend told him he could get 'popcorn lung' from vaping, so he stopped immediately and has been smoking several cigarettes a day since.

Popcorn lung (bronchiolitis obliterans') is a serious lung disease that has been found in some people working in popcorn factories. It is thought to be caused by exposure to a chemical called 'diacetyl' which is used to give popcorn a buttery flavour.

What is the risk of popcorn lung?

Reports that diacetyl was found in some e-liquids created panic that vapers may get popcorn lung (1). However, subsequent studies have shown that the level of diacetyl in the aerosol is 100-750 times LESS than in cigarette smoke (2, 3), and there has NEVER been one reported case of popcorn lung from smoking.

The risks from diacetyl in vapour are so small as to be irrelevant. On the other hand, the risks from continuing to smoke are devastating. My patient has already had two episodes of lung cancer.

Even though the health risk from diacetyl is almost non-existent, responsible manufacturers are removing diacetyl from their e-liquids and many are now labelled 'diacetyl-free'.

The supplier I recommend for my patients has eliminated diacetyl from all their e-liquids which are certified 'diacetyl-free' (Nicopharm).

These scary headlines sell newspapers but are clearly misleading and can cost lives by creating fear about a life-saving treatment.

E-cigarettes are at least 95% less harmful than smoking, even with diacetyl. Returning to smoking is the worst thing any ex-smoking vaper can do for their health.


1) Allen JG. Flavoring Chemicals in E-Cigarettes: Diacetyl, 2,3-Pentanedione, and Acetoin in a Sample of 51 Products, Including Fruit-, Candy-, and Cocktail-Flavored E-Cigarettes. Environ Health Perspect 2016

2) Farsalinos K. Evaluation of Electronic Cigarette Liquids and Aerosol for the Presence of Selected Inhalation Toxins. Nicotine Tob Res 2015

3) Pearce JS. Diacetyl and 2,3-pentanedione exposures associated with cigarette smoking: implications for risk assessment of food and flavoring workers. Critical Reviews in Toxicology 2014

Further information

New Study Finds that Average Diacetyl Exposure from Vaping is 750 Times Lower than from Smoking. The Rest of the Story. Professor Michael Siegel

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